PRI-724

This product is for research use only, not for human use. We do not sell to patients.

PRI-724
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
50mg$850Check With Us
100mg$1350Check With Us
200mg$2025Check With Us

Cat #: V2690 CAS #: 1422253-38-0 Purity ≥ 98%

Description: PRI-724 (an analog of ICG 001 and a prodrug of C-82) is a novel, potent an specific inhibitor of the canonical Wnt signaling pathway in cancer stem cells with potential antineoplastic activity.

References:  2019 Apr 30;10(32):3013-3026

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Product Promise

Promise
Molecular Weight (MW)548.63
Molecular FormulaC33H32N4O4
CAS No.1422253-38-0
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 100 mg/mL (182.3 mM)r
Water: <1 mg/mLr
Ethanol: N/A
Synonymsfoscenvivint; PRI724; PRI-724; PRI 724; C-82 prodrug; ICG-001 analog; ICG001 isomer; ICG-001 isomer; ICG 001 isomer; ICG 001 analog; ICG001 analog; C 82 prodrug; C 82 prodrug;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.8227 mL9.1136 mL18.2272 mL36.4544 mL
5mM0.3645 mL1.8227 mL3.6454 mL7.2909 mL
10mM0.1823 mL0.9114 mL1.8227 mL3.6454 mL
20mM0.0911 mL0.4557 mL0.9114 mL1.8227 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.