KY02111 (KY 02111; KY-02111) is a potent and selective inhibitor of the Wnt signaling pathway with important biological activity.

XAV-939 (also called NVP-XAV 939; XAV939; NVP XAV939; XAV-939) is a potent inhibitor of the TNKS (Tankyrase) with IC50 values of 0.011 and 0.004 μM for inhibiting TNKS1 and TNKS2 respectively.

Wnt-C59 (also called Wnt-C 59; C59; Wnt-C-59; C-59) is a novel, highly potent and orally bioactive PORCN (porcupine) inhibitor with potential antineoplastic activity.

IWR-1-endo (also known as IWR 1-endo; IWR1; IWR-1) is a potent tankyrase inhibitor of the Wnt pathway with potential antitumor activity.

IWP-2 (IWP 2, IWP2) is a novel and potent inhibitor of Wnt processing and secretion (specifically, Porcn-mediated Wnt palmitoylation) with potential antineoplastic activity.

LF3 is a specific antagonist of the β-Catenin/TCF4 interaction with antitumor activity; it acts by disrupting the interaction between β-catenin and TCF4 with an IC50 of 1.65 μM.

WIKI4 (WIKI 4; WIKI-4) is a novel and potent Tankyrase inhibitor with potential anticancer activity.

ICG-001 (ICG001; ICG 001) is a novel and potent inhibitor of β-catenin/TCF mediated transcription.

IWP-L6 (IWPL6; IWPL-6; Porcn Inhibitor III ) is an inhibitor of Porcn (EC50 = 0.5 nM), which is also known as Porcupine and is an enzyme catalyzing the palmitoylation of Wnt proteins.

LGK-974 (formerly known as WNT-974; LGK-974 and NVP-LGK974) is a novel potent, orally bioavailable and specific/selective PORCN (Porcupine) inhibitor with potential anticancer activity.