Xylazine
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 10g | $200 | Check With Us |
| 20g | $300 | Check With Us |
| 50g | $470 | Check With Us |
: Cat #: V28307 CAS #: 7361-61-7 Purity ≥ 98%
Description: Xylazine, an analogue of clonidine, is an α2-Adrenergic receptor agonist used for the treatment of sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other non-human mammals.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 220.33 |
|---|---|
| Molecular Formula | C12H16N2S |
| CAS No. | 7361-61-7 |
| Protocol | In Vivo | Xylazine (5.2 mg/kg; intraperitoneal injection; for 10-60 minutes; male Sprague-Dawley rats) administration alters mRNA expression and protein phosphorylation levels of AMPK signaling molecules, suggesting that the LKB1-AMPK pathway plays a role in the sedative and tranquilizing effects in the CNS caused by Xylazine treatment |
|---|---|---|
| Animal model | Male Sprague-Dawley rats (160-180 g) | |
| Dosages | 5.2 mg/kg | |
| Administration | Intraperitoneal injection; for 10 minutes, 20 minutes, 40 minutes or 60 minutes |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 4.5386 mL | 22.6932 mL | 45.3865 mL | 90.7729 mL |
| 5mM | 0.9077 mL | 4.5386 mL | 9.0773 mL | 18.1546 mL |
| 10mM | 0.4539 mL | 2.2693 mL | 4.5386 mL | 9.0773 mL |
| 20mM | 0.2269 mL | 1.1347 mL | 2.2693 mL | 4.5386 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.