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VPS34-IN1

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VPS34-IN1
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$625Check With Us
250mg$900Check With Us
500mg$1350Check With Us
email: [email protected]        [email protected]

Cat #: V28052 CAS #: 1383716-33-3 Purity ≥ 99%

Description: VPS34-IN1 (VPS34-IN-1) is a novel and potent Vps34 (vacuolar protein sorting 34) inhibitor with potential antitumor activity.

References: Ivan Cornella Taracido, et al. Bi-heteroaryl compounds as vps34 inhibitors. WO2012085815A1.

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Molecular Weight (MW)425.91
Molecular FormulaC21H24ClN7O
CAS No.1383716-33-3
SMILES CodeOC(C)(C)CNC(N=C1CC2CC2)=NC=C1C3=CC=NC(NC4=CC=NC(Cl)=C4)=N3 
SynonymsVPS34IN1, VPS34 IN1, VPS34-IN
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.3479 mL11.7396 mL23.4791 mL46.9583 mL
5mM0.4696 mL2.3479 mL4.6958 mL9.3917 mL
10mM0.2348 mL1.1740 mL2.3479 mL4.6958 mL
20mM0.1174 mL0.5870 mL1.1740 mL2.3479 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
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Volume(start)
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.