Voxtalisib Analog (SAR245409 Analog, XL765 Analog)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
250mg	$1050	Check With Us
500mg	$1650	Check With Us
1g	$2475	Check With Us

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Cat #: V0119 CAS #: 1349796-36-6 Purity ≥ 98%

Description: Voxtalisib analogue (also known as PI3K-IN-1, SAR-245409 Analog, XL-765 Analog), a Voxtalisib derivative, is a novel, potent and orally bioavailable dual inhibitor of mTOR/PI3K with potential anticancer activity.

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Physicochemical and Storage Information
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Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	599.662
Molecular Formula	C31H29N5O6S
CAS No.	1349796-36-6
SMILES Code	O=C(NC1=CC=C(S(=O)(NC2=NC3=CC=CC=C3N=C2NC4=CC(OC)=CC(OC)=C4)=O)C=C1)C5=CC=C(C)C(OC)=C5
Synonyms	Voxtalisib-Analog; XL765-Analog; XL 765-Analog; XL-765-Analog; SAR245409-Analog; SAR245409-Analog; SAR 245409-Analog

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.6676 mL	8.3380 mL	16.6761 mL	33.3521 mL
5mM	0.3335 mL	1.6676 mL	3.3352 mL	6.6704 mL
10mM	0.1668 mL	0.8338 mL	1.6676 mL	3.3352 mL
20mM	0.0834 mL	0.4169 mL	0.8338 mL	1.6676 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.