UNC1079 | CAS 1418741-86-2

UNC1079

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
5mg	$165	3-6 Days
10mg	$220	3-6 Days
25mg	$450	3-6 Days
50mg	$750	3-6 Days
100mg	$1250	3-6 Days
250mg	$2150	3-6 Days

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Cat #: V3021 CAS #: 1418741-86-2 Purity ≥ 98%

Description: UNC1079, the piperidine analog of UNC1021, is a structurally similar but significantly less potent inhibitor for use as a negative control in cellular studies. It is used as a chemical probe for the methyllysine (Kme) reading function of L3MBTL3, a member of the malignant brain tumor (MBT) family of chromatin-interacting transcriptional repressors. The low anticipated affinity of UNC1079 was confirmed, as it demonstrated an activity versus L3MBTL3 of > 10 μM by AlphaScreen, which is >1000-fold weaker than UNC1215. UNC1079 also displays weak binding by ITC.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	466.66
Molecular Formula	C28H42N4O2
CAS No.	1418741-86-2
Storage	-20℃ for 3 years in powder form
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 10mM
	Water: <1 mg/mL
	Ethanol:
SMILES Code	O=C(N1CCC(N2CCCCC2)CC1)C3=CC=C(C(N4CCC(N5CCCCC5)CC4)=O)C=C3
Synonyms	UNC1079; UNC 1079; UNC-1079

Protocol	In Vitro	In vitro activity: Kinase Assay: Cell Assay:

These protocols are for reference only. InvivoChem does not independently validate these methods.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.1429 mL	10.7144 mL	21.4289 mL	42.8578 mL
5mM	0.4286 mL	2.1429 mL	4.2858 mL	8.5716 mL
10mM	0.2143 mL	1.0714 mL	2.1429 mL	4.2858 mL
20mM	0.1071 mL	0.5357 mL	1.0714 mL	2.1429 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.