Tropisetron (SDZ-ICS-930)

This product is for research use only, not for human use. We do not sell to patients.

Tropisetron (SDZ-ICS-930)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
2g$350Check With Us
5g$500Check With Us
10g$750Check With Us

Cat #: V28890 CAS #: 89565-68-4 Purity ≥ 99%

Description: Tropisetron (also known as ICS 205-930) is a novel, potent and selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist, used to treat nausea and vomiting following chemotherapy.

References: Macor JE, et al. The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective alpha7 nicotinic receptor partial agonist. Bioorg Med Chem Lett. 2001 Feb 12;11(3):319-21.

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Molecular Weight (MW)284.35
Molecular FormulaC17H20N2O2
CAS No.89565-68-4
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.5168 mL17.5840 mL35.1679 mL70.3359 mL
5mM0.7034 mL3.5168 mL7.0336 mL14.0672 mL
10mM0.3517 mL1.7584 mL3.5168 mL7.0336 mL
20mM0.1758 mL0.8792 mL1.7584 mL3.5168 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.