Tolazoline
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 10g | $250 | Check With Us |
| 50g | $450 | Check With Us |
| 100g | $675 | Check With Us |
: Cat #: V4217 CAS #: 59-98-3 Purity ≥ 98%
Description: Tolazoline is a potent, non-selective competitive α-adrenergic receptor antagonist.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 160.21 |
|---|---|
| Molecular Formula | C10H12N2 |
| CAS No. | 59-98-3 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: >10 mg/mLr |
| Water: N/Ar | |
| Ethanol: N/A | |
| Synonyms | Imidaline; NSC-35110; NSC35110; NSC 35110; Tolazoline, Benzalolin, Divascol, Pridazole, Priscol, Priscoline |
| Protocol | In Vitro | Tolazoline (Imidaline) can be synthesized by the heterocyclation of the ethyl ester of iminophenzylacetic acid with ethylene diamine, which forms the desired product. The structure of Tolazoline (Imidaline) is strikingly similar to α-adrenergic agonists, which are antiedema sympathomimetics. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 6.2418 mL | 31.2090 mL | 62.4181 mL | 124.8362 mL |
| 5mM | 1.2484 mL | 6.2418 mL | 12.4836 mL | 24.9672 mL |
| 10mM | 0.6242 mL | 3.1209 mL | 6.2418 mL | 12.4836 mL |
| 20mM | 0.3121 mL | 1.5605 mL | 3.1209 mL | 6.2418 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.