TLR7/8 agonist-5d
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $900 | Check With Us |
| 250mg | $1600 | Check With Us |
| 500mg | $2400 | Check With Us |
: Cat #: V16508 CAS #: 1620278-72-9 Purity ≥ 99%
Description: TLR7/8 agonist-5d is a novel and potent TLR7/8 agonist.
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| Molecular Weight (MW) | 432.39 |
|---|---|
| Molecular Formula | C22H27Cl2N5 |
| CAS No. | 1620278-72-9 |
| SMILES Code | NC1=NC2=CC=CC=C2C3=C1N=C(CC4=CC=C(CN)C=C4)N3CCCC.[H]Cl.[H]Cl |
| Synonyms | TLR7/8 agonist-5d; TLR7/8 agonist5d; TLR7/8 agonist 5d |
| Protocol | In Vitro | TLR7/8 agonist 1 (Compound 5d) shows prominent immunostimulatory activities. TLR7/8 agonist 1 serves as a convenient precursor for the covalent attachment of fluorophores without significant loss of activity. TLR7/8 agonist 1 retains TLR7-agonistic activity with an EC50 of 20 nM. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.3127 mL | 11.5636 mL | 23.1273 mL | 46.2545 mL |
| 5mM | 0.4625 mL | 2.3127 mL | 4.6255 mL | 9.2509 mL |
| 10mM | 0.2313 mL | 1.1564 mL | 2.3127 mL | 4.6255 mL |
| 20mM | 0.1156 mL | 0.5782 mL | 1.1564 mL | 2.3127 mL |
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Step One: Enter information below
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Step Two: Enter the in vivo formulation
%DMSO
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%ddH2O
Calculation Results:
Working concentration:
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Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
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mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.