TG100713

This product is for research use only, not for human use. We do not sell to patients.

TG100713
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$750Check With Us
500mg$1250Check With Us
1g$1875Check With Us

Cat #: V0142 CAS #: 925705-73-3 Purity ≥ 98%

Description: TG100713 is a novel and potent pan-PI3K (phosphatidylinositol 3-kinase) inhibitor with potential anti-inflammatory activity.

References: Doukas J, et, al. Phosphoinositide 3-kinase gamma/delta inhibition limits infarct size after myocardial ischemia/reperfusion injury. Proc Natl Acad Sci U S A. 2006 Dec 26;103(52):19866-71.

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Product Promise

Promise
Molecular Weight (MW)254.25
Molecular FormulaC12H10N6O
CAS No.925705-73-3
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 2 mg/mL (7.86 mM)r
Water:<1 mg/mLr
Ethanol: <1 mg/mL
SMILES CodeOC1=CC=CC(C2=NC3=C(N)N=C(N)N=C3N=C2)=C1
SynonymsTG100713; TG-100713; TG 100713
ProtocolIn VitroTG100713 (10 μM; 48 or 72 h) strongly inhibits endothelial cell (EC) proliferation.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.9331 mL19.6657 mL39.3314 mL78.6627 mL
5mM0.7866 mL3.9331 mL7.8663 mL15.7325 mL
10mM0.3933 mL1.9666 mL3.9331 mL7.8663 mL
20mM0.1967 mL0.9833 mL1.9666 mL3.9331 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.