Terazosin HCl dihydrate
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 2g | $590 | Check With Us |
| 5g | $950 | Check With Us |
| 10g | $1425 | Check With Us |
: Cat #: V1147 CAS #: 70024-40-7 Purity ≥ 98%
Description: Terazosin HCl dihydrate (Hytrin; A-45975; A45975), the hydrochloride salt and dihydrated form of terazosin, is a potent and selective α1-adrenoceptor antagonist with antihypertensive effects.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 459.92 |
|---|---|
| Molecular Formula | C19H25N5O4.HCl.2H2O |
| CAS No. | 70024-40-7 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: > 10 mMr |
| Water: N/Ar | |
| Ethanol: N/A | |
| Solubility In Vivo | Chemical Name: Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)-, monohydrochloride InChi Key: IWSWDOUXSCRCKW-UHFFFAOYSA-N InChi Code: InChI=1S/C19H25N5O4.ClH/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22);1H SMILES Code: O=C(N1CCN(C2=NC(N)=C3C=C(OC)C(OC)=CC3=N2)CC1)C4OCCC4.[H]Cl |
| Synonyms | Terazosin hydrochloride; Hytrin; A-45975; A45975; Terazosin HCl hydrate; A 45975; Terazosin HCl dihydrate |
| Protocol | In Vitro | Terazosin does not discriminate cloned α1-adrenoceptor subtypes transiently expressed in COS cells |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.1743 mL | 10.8715 mL | 21.7429 mL | 43.4858 mL |
| 5mM | 0.4349 mL | 2.1743 mL | 4.3486 mL | 8.6972 mL |
| 10mM | 0.2174 mL | 1.0871 mL | 2.1743 mL | 4.3486 mL |
| 20mM | 0.1087 mL | 0.5436 mL | 1.0871 mL | 2.1743 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
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Volume(start)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.