TDZD-8 (NP-01139)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $600 | Check With Us |
| 1g | $950 | Check With Us |
| 5g | $2405 | Check With Us |
: Cat #: V0222 CAS #: 327036-89-5 Purity ≥ 98%
Description: TDZD-8 (NP01139; GSK3 Inhibitor I) is a novel, potent and non-ATP competitive GSK-3β (glycogen synthase kinase-3beta) inhibitor with the potential for treating neurodegenerative diseases such as PD (parkinson disease).
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 222.26 |
|---|---|
| Molecular Formula | C10H10N2O2S |
| CAS No. | 327036-89-5 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 44.5 mg/mL (200.2 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 44.5 mg/mL (200.2 mM) | |
| Solubility In Vivo | O=C(N1CC2=CC=CC=C2)N(C)SC1=O |
| Synonyms | NP-01139; NP 01139; NP01139; TDZD-8; TDZD8; TDZD 8. GSK3 Inhibitor I |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 4.4992 mL | 22.4962 mL | 44.9924 mL | 89.9847 mL |
| 5mM | 0.8998 mL | 4.4992 mL | 8.9985 mL | 17.9969 mL |
| 10mM | 0.4499 mL | 2.2496 mL | 4.4992 mL | 8.9985 mL |
| 20mM | 0.2250 mL | 1.1248 mL | 2.2496 mL | 4.4992 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.