BRD0705 is a novel, potent, paralog selective and orally bioactive glycogen synthase kinase 3α (GSK3α) inhibitor with an IC50 of 66 nM and a Kd of 4.8 μM.

AR-A014418 (AR 0133418; SN4521; GSK-3β inhibitor VIII; AR 014418) is a novel, potent, ATP-competitive, and selective inhibitor of GSK3β (Glycogen Synthase Kinase 3β) with the potential for neurodegenerative diseases.

BIO-acetoxime (also known as GSK-3 Inhibitor X; BIA), a synthetic derivative of a compound from the Mediterranean mollusk Hexaplex trunculus, is a novel, potent and selective dual inhibitor of GSK3α/β (glycogen synthase kinase-3) with potential anti-infection and anticonvulsant as well as anticancer effects.

AZD1080 is a selective, potent, orally bioactive, and brain permeable GSK3 (glycogen synthase kinase-3) inhibitor with neuroprotective effects.

Laduviglusib (CHIR-99021; CT99021 or CHIR-911) HCl is the hydrochloride salt of CHIR-99021, which is a potent and orally available GSK-3α/β (glycogen synthase kinase 3α/β) inhibitor with IC50 of 10 nM/6.7 nM in cell-free assays; CHIR-99021 was proved to promote self-renewal and maintain pluripotency of both B6 and BALB/c ES cells via stabilizing the downstream effectors […]

1-Azakenpaullone (1-Akp), an analog of kenpaullone, is a novel, ATP-competitive and selective inhibitor of GSK-3β (glycogen synthase kinase 3β) with potential antidiabetic and neuroprotective activities.

SB216763 is a novel, potent and selective GSK-3 (glycogen synthase kinase-3) inhibitor with anti- inflammatory activiity and neuro-protective effects as it can promote DNA repair in ischemic retinal neurons.

Laduviglusib (CHIR-99021; CT99021; CT 99021) is a novel, potent and orally bioavailable inhibitor of GSK-3α/β (glycogen synthase kinase 3α/β) with the potential to treat type 2 diabetes.

TWS119, a pyrrolopyrimidine compound, is a novel, potent and selective/specific GSK-3β (Glycogen synthase kinase-3β) inhibitor with potential usefulness for in vivo stem cell biology and therapy.

Indirubin (also known as NSC-105327; Couroupitine B) is a potent and selective inhibitor of CDK (cyclin-dependent kinases) and GSK-3β (glycogen synthase kinase-3) with potential antitumor activity.