TCID
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
100mg | $560 | Check With Us |
500mg | $1550 | Check With Us |
1g | $2325 | Check With Us |
Cat #: V1325 CAS #: 30675-13-9 Purity ≥ 98%
Description: TCID (4,5,6,7-tetrachloro-1H-indene-1,3(2H)-dione) is a novel and potent DUB (deubiquitinylating enzymes) inhibitor that inhibits ubiquitin C-terminal hydrolase L3 with an IC50 of 0.6 μM.
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Molecular Weight (MW) | 283.92 |
---|---|
Molecular Formula | C9H2Cl4O2 |
CAS No. | 30675-13-9 |
Storage | -20℃ for 3 years in powder formr |
-80℃ for 2 years in solvent | |
Solubility In Vitro | DMSO: 23 mg/mL (81.0 mM)r |
Water:<1 mg/mLr | |
Ethanol: <1 mg/mL | |
Synonyms | 4,5,6,7-tetrachloro-1H-indene-1,3(2H)-dione |
Protocol | In Vitro | TCID (4,5,6,7-Tetrachloroindan-1,3-dione; compound 11) inhibits UCH-L1 with an IC50 of 75 μM |
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These protocols are for reference only. InvivoChem does not
independently validate these methods.
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 3.5221 mL | 17.6106 mL | 35.2212 mL | 70.4424 mL |
5mM | 0.7044 mL | 3.5221 mL | 7.0442 mL | 14.0885 mL |
10mM | 0.3522 mL | 1.7611 mL | 3.5221 mL | 7.0442 mL |
20mM | 0.1761 mL | 0.8805 mL | 1.7611 mL | 3.5221 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
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Volume(start)
=
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
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V1
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.