Tariquidar dimesylate

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
250mg	$750	To Be Confirmed
500mg	$1250	To Be Confirmed
1g	$1875	To Be Confirmed

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Cat #: V1756 CAS #: 625375-84-0 Purity ≥ 98%

Description: Tariquidar dimesylate (formerly known as XR9576; D06008; XR-9576; D-06008), the dimesylate salt of Tariquidar, is a novel potent and selective noncompetitive inhibitor of P-glycoprotein (P-gp) with potential antitumor activity.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	838.94
Molecular Formula	C40H46N4O12S2
CAS No.	625375-84-0
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: ≥ 296 mg/mLr
	Water: < 8.9 mg/mLr
	Ethanol: < 8.9 mg/mL
Solubility In Vivo	O=C(C1=CC2=CC=CC=C2N=C1)NC3=CC(OC)=C(OC)C=C3C(NC4=CC=C(CCN5CC6=C(C=C(OC)C(OC)=C6)CC5)C=C4)=O.OS(=O)(C)=O.OS(=O)(C)=O
Synonyms	XR 9576 dimesylate, D06008, XR9576 dimesylate, D 06008, XR-9576, Tariquidar dimesylate; Tariquidar dimesilate; D-06008 dimesylate

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.1920 mL	5.9599 mL	11.9198 mL	23.8396 mL
5mM	0.2384 mL	1.1920 mL	2.3840 mL	4.7679 mL
10mM	0.1192 mL	0.5960 mL	1.1920 mL	2.3840 mL
20mM	0.0596 mL	0.2980 mL	0.5960 mL	1.1920 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.