T16Ainh-A01
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $550 | Check With Us |
| 250mg | $850 | Check With Us |
| 500mg | $1275 | Check With Us |
: Cat #: V5120 CAS #: 552309-42-9 Purity ≥ 98%
Description: T16Ainh-A01 is an aminophenylthiazole analog acting as a novel and potent transmembrane protein 16A (TMEM16A) inhibitor which inhibits TMEM16A-mediated chloride currents with an IC50 value of ~1 µM.
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| Molecular Weight (MW) | 416.52 |
|---|---|
| Molecular Formula | C₁₉H₂₀N₄O₃S₂ |
| CAS No. | 552309-42-9 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent |
| Protocol | In Vitro | T16Ainh-A01 (0.3-30 μM) significantly reduces both inward and outward components of IClCa, and inhibits IClCa in RUICC without significantly affecting L-type Ca2+ current |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.4008 mL | 12.0042 mL | 24.0085 mL | 48.0169 mL |
| 5mM | 0.4802 mL | 2.4008 mL | 4.8017 mL | 9.6034 mL |
| 10mM | 0.2401 mL | 1.2004 mL | 2.4008 mL | 4.8017 mL |
| 20mM | 0.1200 mL | 0.6002 mL | 1.2004 mL | 2.4008 mL |
The molarity calculator equation
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The dilution calculator equation
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Step One: Enter information below
Dosage mg/kg
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Step Two: Enter the in vivo formulation
%DMSO
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%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
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mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.