Synephrine HCl
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 10g | $350 | Check With Us |
| 25g | $550 | Check With Us |
| 50g | $825 | Check With Us |
: Cat #: V1139 CAS #: 5985-28-4 Purity ≥ 98%
Description: Synephrine HCl (Sympatol; oxedrine), the hydrochloride salt of synephrine which is a naturally occuring protoalkaloid extracted from bitter orange and other citrus species, is commonly used for weight loss.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 203.67 |
|---|---|
| Molecular Formula | C9H13NO2.HCl C9H13NO2 |
| CAS No. | 5985-28-4 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 14 mg/mL (68.7 mM)r |
| Water: 41 mg/mL (201.3 mM)r | |
| Ethanol: 4 mg/mL (19.6 mM) | |
| Solubility In Vivo | Saline: 30 mg/mL |
| Synonyms | Sympatol; oxedrine |
| Protocol | In Vivo | Synephrine (1 mg/kg; oral gavage; for 8 days; PVL and BDL rats) significantly ameliorates the hyperdynamic state in both PVL and BDL rats. The portal venous pressure in PVL and BDL rats, portal tributary blood flow and cardiac index are significantly reduced, while mean arterial pressure and systemic as well as portal territory vascular resistance are enhanced by treatment of Synephrine |
|---|---|---|
| Animal model | Portal vein ligation (PVL) or bile duct ligation (BDL) rats | |
| Dosages | 1 mg/kg per 12 hours | |
| Administration | Oral gavage; for 8 days |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 4.9099 mL | 24.5495 mL | 49.0990 mL | 98.1981 mL |
| 5mM | 0.9820 mL | 4.9099 mL | 9.8198 mL | 19.6396 mL |
| 10mM | 0.4910 mL | 2.4550 mL | 4.9099 mL | 9.8198 mL |
| 20mM | 0.2455 mL | 1.2275 mL | 2.4550 mL | 4.9099 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.