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Sumatriptan Succinate (GR43175)

This product is for research use only, not for human use. We do not sell to patients.

Sumatriptan Succinate (GR43175)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
2g$690Check With Us
5g$1150Check With Us
10g$1725Check With Us

Cat #: V0988 CAS #: 103628-48-4 Purity ≥ 98%

Description: Sumatriptan Succinate (GR-43175; GR43175; Sumatran; Sumax), an approved triptan sulfa drug and a sulfonamide compound, is a selective 5-HT1 receptor agonist used for the treatment of migraine headaches.

References: S J Peroutka, et al. Sumatriptan (GR 43175) interacts selectively with 5-HT1B and 5-HT1D binding sites. Eur J Pharmacol. 1989 Apr 12;163(1):133-6. 

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Product Promise

Promise
Molecular Weight (MW)413.49
Molecular FormulaC14H21N3O2S·C4H6O4
CAS No.103628-48-4
Storage-20℃ for 3 years in powder formrr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 83 mg/mL (200.7 mM)rr
Water: <1 mg/mLrr
Ethanol: 83 mg/mL (200.7 mM)
SynonymsGR 43175; Sumatriptan; GR-43175; GR43175; Sumatran; Sumax
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.4184 mL12.0922 mL24.1844 mL48.3688 mL
5mM0.4837 mL2.4184 mL4.8369 mL9.6738 mL
10mM0.2418 mL1.2092 mL2.4184 mL4.8369 mL
20mM0.1209 mL0.6046 mL1.2092 mL2.4184 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.