STAT3-IN-1
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $850 | To Be Confirmed |
| 200mg | $1275 | To Be Confirmed |
| 500mg | $2150 | To Be Confirmed |
: Cat #: V31841 CAS #: 2059952-75-7 Purity ≥ 99%
Description: STAT3-IN-1 is a novel, oral and selective STAT3 inhibitor with anticancer activity.
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 475.53 |
|---|---|
| Molecular Formula | C28H29NO6 |
| CAS No. | 2059952-75-7 |
| SMILES Code | O=C(NC1=CC=C(/C=C/C2=CC(OC)=CC(OC)=C2)C=C1)/C=C/C3=CC(OC)=C(OC)C(OC)=C3 |
| Synonyms | STAT3-IN-1; STAT3IN-1; STAT3 IN-1; STAT3-IN1; STAT3-IN 1; STAT3IN1; STAT3 IN 1; STAT3-IN-7d |
| Protocol | In Vitro | STAT3-IN-1 (compound 7d: 0-10 μM, 48 h) inhibits the STAT3 acetylation at lysine 685 and affected its specific genes expressions. |
|---|---|---|
| In Vivo | STAT3-IN-1 (compound 7d: 10, 20 mg/kg, two weeks) arrests tumor growth with low toxicity in mouse-xenograft model. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.1029 mL | 10.5146 mL | 21.0292 mL | 42.0583 mL |
| 5mM | 0.4206 mL | 2.1029 mL | 4.2058 mL | 8.4117 mL |
| 10mM | 0.2103 mL | 1.0515 mL | 2.1029 mL | 4.2058 mL |
| 20mM | 0.1051 mL | 0.5257 mL | 1.0515 mL | 2.1029 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.