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SRT1720 HCL (CAY-10559)

This product is for research use only, not for human use. We do not sell to patients.

SRT1720 HCL (CAY-10559)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$450In Stock
250mg$750In Stock
500mg$1125In Stock
email: [email protected]        [email protected]

Cat #: V0428 CAS #: 1001645-58-4 (HCl salt) Purity ≥ 98%

Description: SRT1720 HCl (formerly known as CAY10559 HCl), the hydrochloride salt of SRT1720, is a novel, potent and selective SIRT1 (Sirtuin 1) activator with potential anticancer activity and is a promising new therapeutic agent for treating type 2 diabetes.

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Molecular Weight (MW)506.02
Molecular FormulaC25H23N7OS.HCl
CAS No.1001645-58-4 (HCl salt)
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 38 mg/mL (75.1 mM)r
Water: <1 mg/mLr
Ethanol: <1 mg/mL
Solubility In Vivo30% PEG400+0.5% Tween80+5% propylene glycol: 30 mg/mL
SynonymsSRT1720; CAY-10559 HCl; CAY10559; CAY 10559; SRT-1720 HCl, SRT-1720 hydrochloride; SRT1720 HCl; SRT-1720; SRT 1720; SIRT-1933; SIRT 1933; SIRT1933 HCl; CAY-10559;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.9762 mL9.8810 mL19.7621 mL39.5241 mL
5mM0.3952 mL1.9762 mL3.9524 mL7.9048 mL
10mM0.1976 mL0.9881 mL1.9762 mL3.9524 mL
20mM0.0988 mL0.4941 mL0.9881 mL1.9762 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
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Volume(start)
V1
 
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Concentration(final)
C2
 
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.