Spiperone

This product is for research use only, not for human use. We do not sell to patients.

Spiperone
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$400To Be Confirmed
500mg$650To Be Confirmed
1g$975To Be Confirmed

Cat #: V15137 CAS #: 749-02-0 Purity ≥ 99%

Description: Spiperone ( E-525; R-5147; Spiroperidol) is a novel and potent antipsychotic agent acting as a dopamine D2, serotonin 5-HT1A, and serotonin 5-HT2A antagonist with the potential for neurology diseases.

References: Metwally KA, et al. Spiperone: influence of spiro ring substituents on 5-HT2A serotonin receptor binding. J Med Chem. 1998;41(25):5084-5093.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)395.47
Molecular FormulaC23H26FN3O2
CAS No.749-02-0
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.5286 mL12.6432 mL25.2864 mL50.5727 mL
5mM0.5057 mL2.5286 mL5.0573 mL10.1145 mL
10mM0.2529 mL1.2643 mL2.5286 mL5.0573 mL
20mM0.1264 mL0.6322 mL1.2643 mL2.5286 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.