Sertindole
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $750 | To Be Confirmed |
| 500mg | $1250 | To Be Confirmed |
| 1g | $1875 | To Be Confirmed |
: Cat #: V6700 CAS #: 106516-24-9 Purity ≥ 99%
Description: Sertindole (Sertindolum; Lu 23-174) is a potent antipsychotic medication and a neuroleptic drug.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 440.94 |
|---|---|
| Molecular Formula | C24H26ClFN4O |
| CAS No. | 106516-24-9 |
| Protocol | In Vitro | Sertindole (0-100 μM; 48 h) attenuates proliferation of breast cancer cells. Sertindole (0.8-27.6 μM; 48 h) inhibits proliferation toward many cancers in vitro. Sertindole (5 μΜ and 10 μΜ; 24 h) attenuates migration of breast cancer cells |
|---|---|---|
| In Vivo | Sertindole (oral gavage; 10 mg/kg; once daily; 12 d) shows anti-tumor activity in vivo | |
| Animal model | Immune-deficient Balb/c mice implanted MDA-MB-231 human TNBC cells | |
| Dosages | 10 mg/kg | |
| Administration | Oral gavage; 10 mg/kg; once daily; 12 days |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.2679 mL | 11.3394 mL | 22.6788 mL | 45.3576 mL |
| 5mM | 0.4536 mL | 2.2679 mL | 4.5358 mL | 9.0715 mL |
| 10mM | 0.2268 mL | 1.1339 mL | 2.2679 mL | 4.5358 mL |
| 20mM | 0.1134 mL | 0.5670 mL | 1.1339 mL | 2.2679 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.