Serotonin HCl
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 1g | $150 | Check With Us |
| 5g | $300 | Check With Us |
| 10g | $450 | Check With Us |
: Cat #: V0993 CAS #: 153-98-0 Purity ≥ 98%
Description: Serotonin HCl (5-HT HCl; 5-Hydroxytryptamine), the hydrochloride salt of Serotonin, is an endogenous monoamine neurotransmitter found in the brain and also an endogenous agonist of 5-HT receptor.
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| Molecular Weight (MW) | 212.68 |
|---|---|
| Molecular Formula | C10H12N2O.HCl |
| CAS No. | 153-98-0 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 43 mg/mL (202.2 mM)r |
| Water: 43 mg/mL (202.2 mM)r | |
| Ethanol: 2 mg/mL (9.4 mM) | |
| Synonyms | 5-HT HCl; 5-Hydroxytryptamine hydrochloride; 5-HT hydrochloride |
| Protocol | In Vitro | Serotonin hydrochloride is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin hydrochloride also inhibits catechol O-methyltransferase (COMT), an enzyme that contributes to modultion the perception of pain, via non-competitive binding to the site bound by catechol substrates with a binding affinity comparable to the binding affinity of catechol itself (Ki= 44 μM). Results show that addition of 100 μM of Serotonin hydrochloride decreases the reaction velocity of COMT |
|---|---|---|
| In Vivo | Serotonin hydrochloride produces robust hypersensitivity compare to saline-treated controls (p<0.001) |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 4.7019 mL | 23.5095 mL | 47.0190 mL | 94.0380 mL |
| 5mM | 0.9404 mL | 4.7019 mL | 9.4038 mL | 18.8076 mL |
| 10mM | 0.4702 mL | 2.3509 mL | 4.7019 mL | 9.4038 mL |
| 20mM | 0.2351 mL | 1.1755 mL | 2.3509 mL | 4.7019 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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Volume
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The dilution calculator equation
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Volume(start)
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This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.