Sematilide HCl
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $1080 | Check With Us |
| 500mg | $1550 | Check With Us |
| 1g | $2325 | Check With Us |
: Cat #: V3851 CAS #: 101526-62-9 Purity ≥ 98%
Description: Sematilide (formerly known as CK-1752) is a novel class III antiarrhythmic agent.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 349.87 |
|---|---|
| Molecular Formula | C14H24ClN3O3S |
| CAS No. | 101526-62-9 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: >10 mMr |
| Water: N/Ar | |
| Ethanol: N/A | |
| SMILES Code | O=C(NCCN(CC)CC)C1=CC=C(NS(=O)(C)=O)C=C1.[H]Cl |
| Synonyms | CK-1752A HCl; CK1752A; CK 1752A; CK-1752 HCl; CK1752; CK 1752; Sematilide hydrochloride; Sematilide HCl; Sematilide hydrochloride; Sematilide; |
| Protocol | In Vitro | Application of 10, 30, 100 and 300 μM Sematilide causes a concentration-dependent inhibition of the delayed rectifier K+ current (IC50=25 μM) |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.8582 mL | 14.2910 mL | 28.5820 mL | 57.1641 mL |
| 5mM | 0.5716 mL | 2.8582 mL | 5.7164 mL | 11.4328 mL |
| 10mM | 0.2858 mL | 1.4291 mL | 2.8582 mL | 5.7164 mL |
| 20mM | 0.1429 mL | 0.7146 mL | 1.4291 mL | 2.8582 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.