This product is for research use only, not for human use. We do not sell to patients.
| Size | Price | Stock |
|---|---|---|
| 2g | $400 | Check With Us |
| 5g | $780 | Check With Us |
| 10g | $1170 | Check With Us |
: Cat #: V4540 CAS #: 1369773-39-6 Purity ≥ 98%
Description: Sacubitril hemicalcium (also known as AHU377; AHU-377; Entresto), the hemicalcium salt of Sacubitril which is a component of the heart failure medicine LCZ696 (sacubitril/valsartan), is a novel and potent NEP (neutral endopeptidase 24.11) inhibitor with an IC50 of 5 nM.
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| Molecular Weight (MW) | 861.06 |
|---|---|
| Molecular Formula | C48H56CaN2O10 |
| CAS No. | 1369773-39-6 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| SMILES Code | O=C(CCC(N[C@H](CC1=CC=C(C=C1)C2=CC=CC=C2)C[C@H](C(OCC)=O)C)=O)[O-].O=C(CCC(N[C@H](CC3=CC=C(C=C3)C4=CC=CC=C4)C[C@H](C(OCC)=O)C)=O)[O-].[Ca+2] |
| Synonyms | LCZ696; LCZ 696; LCZ696; Sacubitril; Entresto; AHU337; AHU-337; AHU 337; |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.1614 mL | 5.8068 mL | 11.6136 mL | 23.2272 mL |
| 5mM | 0.2323 mL | 1.1614 mL | 2.3227 mL | 4.6454 mL |
| 10mM | 0.1161 mL | 0.5807 mL | 1.1614 mL | 2.3227 mL |
| 20mM | 0.0581 mL | 0.2903 mL | 0.5807 mL | 1.1614 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.