Sacubitril hemicalcium (also known as AHU377; AHU-377; Entresto), the hemicalcium salt of Sacubitril which is a component of the heart failure medicine LCZ696 (sacubitril/valsartan), is a novel and potent NEP (neutral endopeptidase 24.11) inhibitor with an IC50 of 5 nM.

Sacubitrilat (formerly known as LBQ-657; LBQ657) is the activated form of Sacubitril (AHU-377; AHU-377; Entresto), which is a novel and potent NEP (neutral endopeptidase 24.11) inhibitor used in combination with valsartan (LCZ696) for treating heart failure.

Sacubitril (formerly known as AHU-377; Entresto) is a novel and potent NEP (neutral endopeptidase 24.11) inhibitor used in combination with valsartan (as LCZ696) for heart failure.

Sacubitril sodium (also known as AHU-377), the sodium salt of Sacubitril, is an NEP (neutral endopeptidase 24.11) inhibitor (IC50 = 5 nM) used as a component of the heart failure medicine LCZ696 (LCZ-696; LCZ 696; Entresto; Sacubitril mixture with Valsartan).