(S)-Tenofovir

This product is for research use only, not for human use. We do not sell to patients.

(S)-Tenofovir
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$600Check With Us
250mg$1150Check With Us
500mg$1725Check With Us

Cat #: V40146 CAS #: 147127-19-3 Purity ≥ 99%

Description: (S)-Tenofovir [known also as (S)-GS 1278], the S-enantiomer of Tenofovir and a less active isomer, is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B (HBV).

References: Murphy RA, et al. Establishment of HK-2 Cells as a Relevant Model to Study Tenofovir-Induced Cytotoxicity. Int J Mol Sci. 2017 Mar 1;18(3).

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Molecular Weight (MW)287.21
Molecular FormulaC9H14N5O4P
CAS No.147127-19-3
SMILES CodeOP(O)(CO[C@@H](C)CN1C=NC2=C(N)N=CN=C12)=O
Synonyms(S)-Tenofovir
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.4818 mL17.4089 mL34.8177 mL69.6355 mL
5mM0.6964 mL3.4818 mL6.9635 mL13.9271 mL
10mM0.3482 mL1.7409 mL3.4818 mL6.9635 mL
20mM0.1741 mL0.8704 mL1.7409 mL3.4818 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.