Rosiglitazone HCl
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 1g | $450 | Check With Us |
| 2g | $750 | Check With Us |
| 5g | $1265 | Check With Us |
: Cat #: V0838 CAS #: 302543-62-0 Purity ≥ 99%
Description: Rosiglitazone HCl (HSDB-7555; BRL-49653; TDZ-01; BRL49653), the hydrochloride salt of Rosiglitazone, is a potent antidiabetic/antihyperglycemic drug of the thiazolidinedione class with anti-inflammatory activities.
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- Related Biological Data
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| Molecular Weight (MW) | 393.89 |
|---|---|
| Molecular Formula | C18H19N3O3S.HCl |
| CAS No. | 302543-62-0 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 79 mg/mL (200.6 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 79 mg/mL (200.6 mM) | |
| Synonyms | Rosiglitazone HCl; Rosiglitazone Hydrochloride; HSDB-7555; BRL-49653 HCl; BRL49653; TDZ-01; BRL 49653; HSDB 7555; HSDB7555; TDZ 01; TDZ01; Rosiglitazone. trade name Avandia. |
| Protocol | In Vitro | Rosiglitazone hydrochloride (0.1-10 μM, 72 h) results in pluripotent C3H10T1/2 stem cell differentiation to adipocytes. |
|---|---|---|
| In Vivo | Rosiglitazone hydrochloride (oral administration, 5 mg/kg, daily for 8 weeks) decreases the serum glucose in diabetic rats. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.5388 mL | 12.6939 mL | 25.3878 mL | 50.7756 mL |
| 5mM | 0.5078 mL | 2.5388 mL | 5.0776 mL | 10.1551 mL |
| 10mM | 0.2539 mL | 1.2694 mL | 2.5388 mL | 5.0776 mL |
| 20mM | 0.1269 mL | 0.6347 mL | 1.2694 mL | 2.5388 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.