Rolipram (ME 3167; ZK 62711; SB 95952)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 1g | $650 | Check With Us |
| 2g | $1050 | Check With Us |
| 5g | $1770 | Check With Us |
: Cat #: V0788 CAS #: 61413-54-5 Purity ≥ 98%
Description: Rolipram (formerly called ME-3167; ZK-62711; SB95952; the racemic mixture of R- and S-rolipram) is a novel, potent and selective phosphodiesterase PDE4 inhibitor with potential anti-inflammatory and anti-depressant activity.
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- Physicochemical and Storage Information
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- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 275.34 |
|---|---|
| Molecular Formula | C16H21NO3 |
| CAS No. | 61413-54-5 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 55 mg/mL (199.8 mM)r |
| Water:<1 mg/mLr | |
| Ethanol: 55 mg/mL (199.8 mM) | |
| Solubility In Vivo | 30% PEG400+0.5% Tween80+5% propylene glycol: 10 mg/L |
| SMILES Code | O=C1NCC(C2=CC=C(OC)C(OC3CCCC3)=C2)C1 |
| Synonyms | ZK-62711; SB 95952; SB95952; SB-95952; ME-3167; ZK-62711; ME3167; ZK62711; ME 3167; ZK 62711 |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.6319 mL | 18.1594 mL | 36.3187 mL | 72.6375 mL |
| 5mM | 0.7264 mL | 3.6319 mL | 7.2637 mL | 14.5275 mL |
| 10mM | 0.3632 mL | 1.8159 mL | 3.6319 mL | 7.2637 mL |
| 20mM | 0.1816 mL | 0.9080 mL | 1.8159 mL | 3.6319 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.