Risperidone Mesylate
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $450 | Check With Us |
| 1g | $650 | Check With Us |
| 5g | $1755 | Check With Us |
: Cat #: V13809 CAS #: 666179-96-0 Purity ≥ 99%
Description: Risperidone mesylate is the mesylate salt of Risperidone (R64766; Risperdal), which is an approved atypical antipsychotic and a blocker of dopamine D2 receptors as well as serotonin 5-HT2 receptors.
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- Related Biological Data
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| Molecular Weight (MW) | 506.59 |
|---|---|
| Molecular Formula | C24H31FN4O5S |
| CAS No. | 666179-96-0 |
| Protocol | In Vitro | Risperidone is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively. Risperidone dose-dependently inhibited the release of IL-12 in mature DCs, while the production of IL-10 is dose-dependently increased by Risperidone. A high dose of risperidone can induce TNF-α release from mature DCs |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.9740 mL | 9.8699 mL | 19.7398 mL | 39.4797 mL |
| 5mM | 0.3948 mL | 1.9740 mL | 3.9480 mL | 7.8959 mL |
| 10mM | 0.1974 mL | 0.9870 mL | 1.9740 mL | 3.9480 mL |
| 20mM | 0.0987 mL | 0.4935 mL | 0.9870 mL | 1.9740 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
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C1
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V1
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.