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REN-1189(CPI-1189)

This product is for research use only, not for human use. We do not sell to patients.

REN-1189(CPI-1189)
For small sizes, please check our retail website as below: www.invivochem.com
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250mg$500Check With Us
500mg$800Check With Us
1g$1200Check With Us
email: [email protected]        [email protected]

Cat #: V13666 CAS #: 183619-38-7 Purity ≥ 98%

Description: REN-1189 is a TNF-a release inhibitor potentially for the treatment of sciatica and postherpetic neuralgia.

References: Müller T. CPI-1189. Centaur. Curr Opin Investig Drugs. 2002 Dec;3(12):1763-7. 

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Molecular Weight (MW)234.29
Molecular FormulaC13H18N2O2
CAS No.183619-38-7
SMILES CodeO=C(NC(C)(C)C)C1=CC=C(NC(C)=O)C=C1
SynonymsREN1189; REN1654; CPI 1189; REN 1189; REN 1654; CPI-1189; REN-1189; REN-1654; CPI1189;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM4.2682 mL21.3411 mL42.6821 mL85.3643 mL
5mM0.8536 mL4.2682 mL8.5364 mL17.0729 mL
10mM0.4268 mL2.1341 mL4.2682 mL8.5364 mL
20mM0.2134 mL1.0671 mL2.1341 mL4.2682 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
=
Concentration
 
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Volume
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.