(R)-baclofen (STX209)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $180 | Check With Us |
| 500mg | $345 | Check With Us |
| 1g | $520 | Check With Us |
: Cat #: V1291 CAS #: 69308-37-8 Purity ≥ 98%
Description: (R)-baclofen (formerly STX-209; STX209; STX 209), a derivative of gamma-aminobutyric acid, is a selective GABAB receptor agonist that has been primarily used to treat spasticity.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 213.66 |
|---|---|
| Molecular Formula | C10H12ClNO2 |
| CAS No. | 69308-37-8 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 8 mg/mL (37.4 mM)r |
| Water:<1 mg/mLr | |
| Ethanol:<1 mg/mL | |
| Synonyms | STX209; STX-209; STX 209; |
| Protocol | In Vivo | (R)-Baclofen (STX209) inhibits audiogenic seizures in Fmr1-knockout mice against the background of C1BL/57 anti-seizures at an effective dose of 6 mg/kg |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 4.6803 mL | 23.4017 mL | 46.8033 mL | 93.6067 mL |
| 5mM | 0.9361 mL | 4.6803 mL | 9.3607 mL | 18.7213 mL |
| 10mM | 0.4680 mL | 2.3402 mL | 4.6803 mL | 9.3607 mL |
| 20mM | 0.2340 mL | 1.1701 mL | 2.3402 mL | 4.6803 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.