exo-IWR-1 is an inactive stereoisomer of Endo-IWR-1,and is used as a negative control of IWR-1 (V1351) which is a potent tankyrase inhibitor of the Wnt pathway with potential antitumor activity.

iCRT3 (iCRT-3) is an inhibitor of Wnt and β-catenin-responsive transcription in the Wnt/wingless signaling pathway with anticancer activity.

Gigantol is a bibenzyl compound derived from several medicinal orchids.

SM04554 (Dalosirvat, Wnt pathway activator 1), a novel activator of Wnt with an IC50s of 28-29 nM, is an experimental drug that shows promise for treating androgenetic alopecia (male pattern baldness).

BML-284 HCl (AMBMP and Wnt agonist 1) is a potent and selective activator of Wnt signaling with anti-inflammatory activity.

SKL2001 (SKL-2001) is a novel and potent agonist of Wnt/β-catenin signaling pathway with antitumor activity.

Prinaberel, formerly known as ERB-041, is a biochemical which acts as a highly selective agonist of the ERβ subtype of the estrogen receptor.

RCM-1 is a novel and potent nontoxic FOXM1 inhibitor, which is able to inhibit goblet cell metaplasia and excessive mucus production.

Pyrvinium is an FDA-approved antihelmintic drug for pinworms, it inhibits WNT pathway signaling.