CCT007093, a thienylidene cyclopentanone, is a potent PPM1D (WIP1) inhibitor with IC50 of 8.4 μM.
(1S,2S,3R)-DT-061 is an isomer/enantiomer of DT-061 (DT061), which is a novel and orally bioavailable activator of protein phosphatase 2A (PP2A) and may be used in the therapy of KRAS-mutant and MYC-driven tumorigenesis.
Licoflavone A is a novel and potent flavonoid.
CPDA [N-[4-(4-chlorobenzyloxy)pyridin-2-yl]-2-(2,6-difluorophenyl)- acetamide] is a novel potent inhibitor of SHIP2 [SH2-containing 5′-inositol phosphatase 2] that can effectively ameliorate insulin resistance in 3T3-L1 adipocytes.
Rosiptor (AQX-1125; AQX1125; AQX 1125) is an orally bioavailable and selective activator of the phosphatase SHIP1 (SH2 domain-containing inositol-5′-phosphatase 1) with potential anti-inflammatory activities.
BAMB-4 (formerly known as ITPKA-IN-C14) is a novel and highly potent membrane-permeable inhibitor of inositol-1,4,5-trisphosphate-3-kinase A (ITPKA) with IC50 of 37 uM in ADP-Glo Assay.
Sal003 is a potent, selective and cell-permeable eIF-2α phosphatase inhibitor.
Raphin1 acetate is a novel and potent inhibitor of the regulatory phosphatase PPP1R15B (R15B).
APS-5 is a chemiluminescent substrate based on 9, 10-dihydroacridine, and is mainly used for ELISA detection of compounds with alkaline phosphatase AP conjugation.
Silydianin is a novel and potent constituent of Silybium marianum.