Telotristat besilate, the besilate salt of telotristat, is an analog of Telotristat ethyl (formerly LX 1032; LX 1606; trade name: Xermelo), which is an orally bioavailable tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity. Telotristat ethyl was approved in 2017 to treat carcinoid syndrome diarrhea.

PNU-282987 S enantiomer hydrochloride is the absolute stereochemistry form of PNU-282987. PNU-282987 S enantiomer hydrochloride is a potent agonist of α7-containing neuronal nicotinic acetylcholine receptors (nAChRs) with Ki of 26 nM for the rat receptor.

NSC-404988 is a chemical intermediate used in organic synthesis

2,2′-Azobis(2-methylpropionitrile), also named as AIBN, 2,2′-Azobis(2-methylpropionitrile)

Lasmiditan HCl (formerly COL-144 HCl, LY-573144 HCl) is a novel and selective 5-HT(1F) receptor agonist with Ki of 2.1 nM versus Ki of 1043 nM and 1357 nM at the 5-HT(1B) and 5-HT(1D) receptors, respectively. For the understanding of migraine pathophysiology, it is very important to note that a selective 5-HT(1F) receptor agonist like lasmiditan […]

RS 127445 maleate is a novel,selective, high affinity and orally bioavailable antagonist of 5-HT2B receptor ( pKi = 9.5).

Seractide,also known as ACTH (1-39) , is a novel and potent endogenous melanocortin receptor 2 (MC2) agonist (EC50 = 57 pM).

Mitiglinide (also known as KAD-1229; S21403) is a Potassiun Channel blocker that is used as a blood glucose-lowering drug, it stimulates insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-cells. Mitiglinide is thought to stimulate insulin secretion by closing the ATP-sensitive K(+) K(ATP) channels in pancreatic beta-cells. Mitiglinide may be potential useful for […]

AA92593（also known as Cy1001）, is a novel and potent selective melanopsin inhibitor.