4-Methyl-2-phenylchromenylium tetrafluoroborate, fluorescent dye

Picrocrocin, a monoterpene glycoside precursor of safranal, is a natural product found in the spice saffron, which comes from the crocus flower. Picrocrocin is a degradation product of the carotenoid zeaxanthin. Picrocrocin exhibits growth inhibitory effects against SKMEL- 2 human malignant melanoma cells by targeting JAK/ STAT5 signaling pathway, cell cycle arrest and mitochondrial mediated […]

N-(2-hydroxy-2-phenylethyl)acetamide, bioactive compound

BDP FL amine HCl, borondipyrromethene dye

Biotin-PEG-Alk, enzyme co-factor

VP-4604, anti-methicillin-resistant Staphylococcus aureus (MRSA) agent

PD-1/PD-L1-IN-14 is a novel small molecule inhibitor of the PD-1/PD-L1 protein-protein interaction (IC50 of = 28 nM) with anticancer and immunomodulatory/immunoregulatory activity. As a bifunctional inhibitor of PD-1/PD-L1 interactions, it inhibits PD-1/PD-L1 interactions and promotes dimerization, internalization, and degradation of PD-L1.

15,16-Epoxy-12R-hydroxylabda-8(17),13(16),14-triene, bioactive compound

N-Acetyl-DL-serine, hydrophobic amino acid

PD-1/PD-L1-IN-16 is a novel small molecule inhibitor of the PD-1/PD-L1 protein-protein interaction (IC50 of = 53 nM) with anticancer and immunomodulatory/immunoregulatory activity.