NMS-P715 HCl, the hydrochloride salt of NMSP715, is a novel, potent, selective and orally bioavailable MPS1 inhibitor with anticancer activity. It selectively reduces cancer cell proliferation, leaving normal cells almost unaffected. NMS-P715 accelerates mitosis and affects kinetochore components localization causing massive aneuploidy and cell death in a variety of tumorally bioavailable cell lines and inhibits […]

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