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Cat #: V33604 CAS #: 1202055-32-0 Purity ≥ 99%
Description: NMS-P715 HCl, the hydrochloride salt of NMSP715, is a novel, potent, selective and orally bioavailable MPS1 inhibitor with anticancer activity. It selectively reduces cancer cell proliferation, leaving normal cells almost unaffected. NMS-P715 accelerates mitosis and affects kinetochore components localization causing massive aneuploidy and cell death in a variety of tumorally bioavailable cell lines and inhibits tumor growth in preclinical cancer models. Inhibiting the SAC could represent a promising new approach to selectively target cancer cells.
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Molecular Weight (MW) | 676.73 |
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Molecular Formula | C₃₅H₃₉F₃N₈O₃ |
CAS No. | 1202055-32-0 |
Solvent volume to be added | Mass (the weight of a compound) | |||
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Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 1.4777 mL | 7.3885 mL | 14.7769 mL | 29.5539 mL |
5mM | 0.2955 mL | 1.4777 mL | 2.9554 mL | 5.9108 mL |
10mM | 0.1478 mL | 0.7388 mL | 1.4777 mL | 2.9554 mL |
20mM | 0.0739 mL | 0.3694 mL | 0.7388 mL | 1.4777 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.