SMS1-IN-1 is a novel and potent sphingomyelin synthase 1 (SMS1) inhibitor

5-Amino-4-oxopentanoic acid phosphate (Aminolevulinic acid phosphate) is an FDA approved and topically used drug for treating actinic keratosis. It is an intermediate in heme biosynthesis and the universal precursor of tetrapyrroles.

Exametazime (hexamethylpropylene amine oxime or HMPAO) is a radiopharmaceutical sold under the trade name Ceretec, and is used by nuclear medicine physicians for the detection of altered regional cerebral perfusion in stroke and other cerebrovascular diseases. It can also be used for the labelling of leukocytes to localise intra-abdominal infections and inflammatory bowel disease.

Biotinyl tyramide is a novel biotin analogue used for tyramide signal amplification (TSA) via catalyzed reporter deposition (CARD), and as a reagent to amplify both immunohistochemical signals and in situ hybridization protocols.

This product is discontinued due to commercial reason. (R)-Nedisertib (M-3814; RMSC-2490484A; M3814; RMSC2490484A), the R-enantiomer of nedisertib, is a novel and potent inhibitor of DNA-dependent protein kinase (DNA-PK) with anticancer activity.

Insulin (human) is an endogenous/naturally occurring polypeptide hormone produced in the pancreas. Its main role is to regulate sugar levels by allowing cells throughout the body to uptake glucose (sugar) and convert it into a form that can be used by these cells for energy. Basically, insulin helps remove sugar from the blood. This helps […]

LTβR-IN-1 is a novel and potent lymphotoxin β receptor (LTβR) inhibitor with an IC50 of 10 μM.

1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid is a natural product isolated from Cordyceps bassiana with various bioactivities such as anti-cancer, anti-oxidative, anti-inflammatory, anti-angiogenic, anti-obesity, anti-diabetic, and anti-nociceptive activities. It can block AP-1-mediated luciferase activity.

4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)piperazine-1-carbothioamide trifluoroacetate is a biochemical compound

3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid; 3-oxoLCA; 3-Oxo-5β-cholan-24-oic Acid; 3-Oxo- 5β-cholanic Acid; 3-Ketolithocholic Acid), a bile acid metabolite, is a major metabolite of lithocholic acid (LCA) formed from LCA by the cytochrome P450 (CYP) isoform CYP3A4. It is an agonist of G protein-coupled bile acid activated receptor 1 (GP-BAR1/TGR5; EC50 = 0.27 μM), vitamin D receptor (VDR; […]