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(R)-Nedisertib (M3814; RMSC2490484A)

This product is for research use only, not for human use. We do not sell to patients.

(R)-Nedisertib (M3814; RMSC2490484A)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5mg$2003-6 Days
25mg$5503-6 Days
50mg$8503-6 Days
email: [email protected]        [email protected]

Cat #: V32430 CAS #: 1637542-32-5 Purity ≥ 99%

Description: This product is discontinued due to commercial reason. (R)-Nedisertib (M-3814; RMSC-2490484A; M3814; RMSC2490484A), the R-enantiomer of nedisertib, is a novel and potent inhibitor of DNA-dependent protein kinase (DNA-PK) with anticancer activity.

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Molecular Weight (MW)481.912
Molecular FormulaC24H21ClFN5O3
CAS No.1637542-32-5
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.0751 mL10.3753 mL20.7507 mL41.5014 mL
5mM0.4150 mL2.0751 mL4.1501 mL8.3003 mL
10mM0.2075 mL1.0375 mL2.0751 mL4.1501 mL
20mM0.1038 mL0.5188 mL1.0375 mL2.0751 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
=
Concentration
 
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Volume
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
×
 
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.