Ureidovaline is a chemical intermediate used for the synthesis of the the anti-HIV drug Ritonavir.
Lacosamide (ADD243037; ADD-243037; ADD 243037; erlosamide; Vimpat) is a marketed anticonvulsant drug used for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain. It acts by enhancing the slow inactivation of voltage gated sodium channels.
RN-1734 (RN1734) is a novel and potent TRPV4 antagonist, acting by completely blocking 4αPDD-mediated activation of TRPV4 with micromolar IC50s for three species (IC50 = 2.3 μM, 5.9 μM, 3.2 μM for hTRPV4, mTRPV4 ,rTRPV4, respectively).
Testosterone acetate is the ester prodrug of Testosterone which is an endogenous hormone. It may be used for impotence, weakness, fatigue, and hypogonadism.
Hydronidone (F-351) is a novel and potent Non-Steroidal Antiinflammatory Drugs (NSAIDs) with antifibrotic activity and the potential for hepatic fibrosis.
Esonarimod is an antirheumatic drug, suppressing lymphocyte activating factor activity or biosynthesis.
Dextrorphan tartrate is a novel and potent glutamate receptor antagonist with the potential for the treatment of stroke. It is an NMDA antagonist and contributes to the psychoactive effects of dextromethorphan. It is the dextrorotatory-stereoisomer of racemorphan, the levo-half being levorphanol. Dextrorphan is produced by O-demethylation of dextromethorphan by CYP2D6.
HT-61 (HT61; HY-50A) is a novel and potent pyrroloquinolone-based antibiotic with potential usefulness in the treatment of staphylococcal infections. HT61 was effective at reducing biofilm viability and was associated with increased expression of cell wall stress and division proteins, confirming its potential as a treatment for S. aureus biofilm infections. HT61 enhances the effect of […]
P7C3-OMe, formerly known as (R)-P7C3-OMe, is an analogue of P7C3 and P3C3-A20. P7C3 Attenuates the Scopolamine-Induced Memory Impairments in C57BL/6J Mice.P7C3-A20 promotes neurogenesis and improves cognitive function after ischemic stroke.
15-Hydroxy Lubiprostone is a halogenated (16,16-difluoro), bioactive lipid and a prostaglandin E analog with the potential to be used as a chloride channel opener for the treatment of gastrointestinal disorder.