p-Valerylphenol is a novel and potent bioactive compound

Phenylethyl alcohol is a novel and potent organic compound

Biphenomycin A is a novel and potent peptide antibiotic

Acetoxycycloheximide is a novel and potent apoptosis inducer

Carmoterol HCl is a novel and potent 2-adrenoceptor agonist

Azido-PEG3-(CH2)3OH is a PEG-based linker containing an azide group and a terminal hydroxyl group. It is used in the synthesis of PROTACs. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydroxyl group enables further derivatization […]

Braco-19 is a novel and potent G-quadruplex ligandthat inhibits tumor growth

Propargyl-PEG4-bromide is a novel and potent PEG analog

RPC425, a conformationally restricted analogues of γ-aminobutyric acid (GABA), is a novel, potent and noncompetitive Inhibitors of the Betaine/γ-Aminobutyric Acid Transporter 1 (BGT1). GT1 has emerged as an interesting target for treating epilepsy due to animal studies that reported anticonvulsant effects for the GAT1/BGT1 selective inhibitor EF1502 and the BGT1 selective inhibitor RPC-425.

BMS-823778 is a novel, potent, orally bioavailable and selective inhibitor of 11-β-hydroxysteroid-dehydrogenase 1 (11βHSD-1). BMS-823778 is a potential therapeutic agent for type 2 diabetes mellitus (T2DM).