Azido-PEG3-(CH2)3OH

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Cat #: V5356 CAS #: 1807512-36-2 Purity ≥ 98%

Description: Azido-PEG3-(CH2)3OH is a PEG-based linker containing an azide group and a terminal hydroxyl group. It is used in the synthesis of PROTACs. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

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Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	233.27
Molecular Formula	C9H19N3O4
CAS No.	1807512-36-2
Synonyms	Azido-PEG3-(CH2)3OH

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	4.2869 mL	21.4344 mL	42.8688 mL	85.7376 mL
5mM	0.8574 mL	4.2869 mL	8.5738 mL	17.1475 mL
10mM	0.4287 mL	2.1434 mL	4.2869 mL	8.5738 mL
20mM	0.2143 mL	1.0717 mL	2.1434 mL	4.2869 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.