AV-105 is a precursor to the synthesis of Florbetapir (18F), which is a positron emission tomography (PET) scanning radiopharmaceutical agent used for PET imaging of neurodegenerative diseases of the brain such as Alzheimer’s disease.

Dilazep diHCl (K-285; AS-05; ), the dihydrochloride salt of dilazep, is a novel and potent vasodilator acting as an adenosine uptake inhibitor with antiarrhythmic activity. Also inhibiting ischemic damage, platelet aggregation, and membrane transport of nucleosides.

TIC10 (imipridone, ONC-201) HCl is a novel, potent, orally bioactive, brain penetrant, and stable tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) inducer which acts by inhibiting Akt and ERK, consequently activating Foxo3a and significantly inducing cell surface TRAIL. TIC10 can inactivate Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the […]

Difetarsone (Diphetarson; Benarsal; RP-4763; RP4763) is a novel and potent antiprotozoal agent that shows effectiveness against Trichuris trichiura (whipworm). It has also been used to treat Entamoeba histolytica infections. Reference: Arch Dis Child. 1974 Jun;49(6):486-8.

SMS2-IN-1 is a highly selective sphingomyelin synthase 2 (SMS2) inhibitor ( IC50 = 6.5 nM).

Isoindigotin is a potential antileukemic agent.

TPT-260 2HCl (R55) is a novel and potent thiophene thiourea analogue

E7107 (E-7107), a semisynthetic pladienolide B derivative, is a first-in-class and potent precursor messenger ribonucleic acid (pre-mRNA) spliceosome inhibitor that targets the Splicing factor 3B subunit 1 (SF3b1) of the spliceosome, and shows significant antitumor activities. It is a semisynthetic derivative of the natural product pladienolide B which was originally isolated from Streptomyces platensis. Development […]

KUN50259, formerly known as DAAO inhibitor-1, is a potent D-amino acid oxidase (DAAO) inhibitor with an IC50 of 0.12 μM. DAAO inhibitor-1 has CAS#2065250-25-9. It is named as KUN50259 according to Hodoodo Chemical Nomenclature (//hodoodo.com/hodoodo-chemical-nomenclature).

Bovine Serum Albumin (BSA) is a globular protein composed of 583-amino acid residues. It has three homologous all-α domains, which are organized in a heart-shaped structure. BSA can be used in a numer of biochemical applications. Referecnes: Biochim Biophys Acta. 2007 Sep;1774(9):1128-38.