IACS-10759 HCl (IACS10759; IACS-010759) was identified as a potent and orally bioavailable inhibitor of complex I of oxidative phosphorylation (OXPHOS) with anticancer activity.

HQNO, secreted by P. aeruginosa, is a novel and potent electron transport chain inhibitor with a Kd of 64 nM for complex III.

FCCP (full name: Carbonyl cyanide-4-(trifluoromethoxy)phenylhydrazone) is an ionophore and often referred to as a mitochondrial uncoupling agent.

MCU-i4 is a negative modulator of of the MCU (mitochondrial calcium uniporter), acting by inhibiting IP3-dependent mitochondrial Ca2+-uptake and maintaining the gatekeeping role of their target.

Idebenone (also known as CV-2619) is a synthetic analog of coenzyme Q10 (CoQ10) and a brain stimulant.

LDC195943 (also known as IMT1) is a novel, potent and highly specific inhibitor of POLRMT (human mitochondrial RNA polymerase) with anticancer activity.

NSC 102533 is a bioactive molecule of the flavonoid class.