Filanesib (formerly also known as ARRY-520) is a novel, potent and synthetic small molecule inhibitor of kinesin spindle protein (KSP) with anticancer activity.

Monastrol is an allosteric inhibitor of the mitotic kinesin Eg5 that exhibits an antiproliferative effect against several cell lines.

EMD534085 (EMD-534085) is a mitotic kinesin inhibitor (IC50 = 8 nM) currently in clinical development for cancer treatment.

(R)-Filanesib, the R-enantiomer of ARRY-520, is a novel and potent kinesin spindle protein (KSP) inhibitor (IC50 = 6 nM) with anticancer activity.