Catalog No:
V0924
CAS No. (CAS Registry Number):
79902-63-9
Description:
Simvastatin (MK0733, Zocor; Synvinolin; Sinvacor; MK-0733; SIM), a marketed anti-hyperlipidemic drug of the statin class, is a lactone prodrug that has to be activated through hydrolysis to the active β-hydroxy acid form, which then acts as a potent and competitive inhibitor of HMG-CoA (3-hydroxy-3-methyl glutaryl coenzyme A) reductase with Ki of 0.1-0.2 nM in cell-free […]