BMS-833923 (also known as XL139; BMS833923; XL-139; BMS 833923) is a novel, potent, selective, and orally bioavailable inhibitor of SMO (Smoothened) with potential antineoplastic activity.

TAK-441 is a novel, orally bioavailable, potent and selective Hedgehog (Hh) signaling pathway inhibitor with acceptable solubility and pharmacokinetic properties.

ALLO-2 is a novel and potent drug-resistant Smoothened (Smo) mutant antagonist that inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM.

Jervine (11-Ketocyclopamine) is a naturally occurring steroidal alkaloid found in rhizomes of Veratrum nigrum and has anti-inflammatory and antioxidant activity.

JK184 is a novel and potent Hedgehog (Hh) pathway inhibitor with IC50 of 30 nM in mammalian cells.

Ciliobrevin A, formerly known as HPI-4 and Hedgehog Pathway Inhibitor 4, is a Hedgehog pathway inhibitor.