Jervine
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $750 | Check With Us |
| 500mg | $1125 | Check With Us |
| 1g | $1685 | Check With Us |
: Cat #: V30496 CAS #: 469-59-0 Purity ≥ 98%
Description: Jervine (11-Ketocyclopamine) is a naturally occurring steroidal alkaloid found in rhizomes of Veratrum nigrum and has anti-inflammatory and antioxidant activity.
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 425.60 |
|---|---|
| Molecular Formula | C27H39NO3 |
| CAS No. | 469-59-0 |
| Protocol | In Vivo | Jervine (orally; 50-400 mg/kg) exerts 50.4-73.5% anti-inflammatory effects in carrageenan induced paw edema |
|---|---|---|
| Animal model | Male Sprague Dawley rats (180-200 g) | |
| Dosages | 50, 100, 200 and 400 mg/kg | |
| Administration | Orally |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.3496 mL | 11.7481 mL | 23.4962 mL | 46.9925 mL |
| 5mM | 0.4699 mL | 2.3496 mL | 4.6992 mL | 9.3985 mL |
| 10mM | 0.2350 mL | 1.1748 mL | 2.3496 mL | 4.6992 mL |
| 20mM | 0.1175 mL | 0.5874 mL | 1.1748 mL | 2.3496 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.