Lactitol monohydrate (CCRIS6315; Lactit; Lactosit Miruhen; NSC-231323; pizensy), the monohydrated form of lactitol and a disaccharide analogue of lactulose, is a naturally occuring sweetener and gastrointestinal agent as well as an osmotic laxative used for the treatment of chronic idiopathic constipation (CIC) in adults.

ANT-3310 sodium (ANT3310) is a novel and covalent Serine β-Lactamase inhibitor of the diazabicyclooctane class with a broad-spectrum of antibacterial activity.

Thiotepa or Thio-TEPA (NSC-6396; AI3 24916; WR45312; Girostan), an approved drug for cancer treatment, is a potent DNA alkylating agent with antitumor activity.

Colistin sulfate (Belcomycin; Polymixin E), originally isolated from B. polymyxa, is a polypeptide antibiotic and apoptosis inducer, also acts as a NADH quinone oxidoreductase inhibitor.

Mecillinam (FL-1060; amdinocillin) is a potent and broad spectrum penicillin antibiotic that binds specifically to penicillin binding protein 2 (PBP2), and is only considered to be active against Gram-negative bacteria.

Clindamycin hydrochloride monohydrate (Clinsol; EC 244-398-6; EC2443986; U-21251; Cleocin, U21251; U 21251 F; Clinacin, Dalacin),the hydrochloride salt and hydrated form of Clindamycin which is a semisynthetic analog of lincomycin and ribosomal translocation / protein inhibitor, is a potent antibiotic acting as a protein synthesis inhibitor.

Protionamide (prothionamide) is a drug /medication of the antiarrhythmic class used in the treatment of cardiac arrhythmias and tuberculosis; has also been tested for use in the treatment of leprosy.

Oleandomycin (PA 775) is a classic macrolide antibiotic produced by strains of Streptomyces that demonstrates antimicrobial activity similar to penicillin and erythromycin. It is structurally closely related to Erythromycin and consists of a macrocyclic lactone ring of 14 carbon atoms with one sugar, oleandrose, and one amino sugar, desoxamine, attached to the lactone ring. The […]

Polymyxin B (also known as Aerosporin, PMB, Poly-RX) is an antibiotic and a cationic surfactant primarily used for resistant gram-negative infections. Polymyxin B sulfate is a mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin […]

Hygromycin B is a novel and potent protein translocation inhibitor.